Department of Built Environment, North Carolina A&T State University, Greensboro, North Carolina, United States of AmericaAbstract: Occupational determinants of health encompass a broad spectrum of workplace factors that wield considerable influence over an individual’s holistic well-being, encompassing physical, mental, and social dimensions. This viewpoint aims to provide an expansive and nuanced examination, evaluation, and definition of these determinants, elucidating the intricate interplay between one’s occupation and their health. Extensive research, including a meticulous review of qualitative and quantitative studies conducted between 2000 and 2023, has been undertaken to delineate occupational hazards prevalent across diverse professions. The findings underscore the pivotal roles played by biological and chemical hazards, alongside the intricate web of occupational and socioeconomic factors, in shaping the health landscape of workers. This comprehensive analysis not only highlights the varied dimensions of occupational health but also sheds light on the multifaceted nature of hazards, emphasizing their significant impact on the well-being of individuals within the workforce.Keywords: Occupational, workplace, health, United StatesCorrespondence: Emmanuel Obeng-Gyasi, PhD, MPH, Department of Built Environment, North Carolina A&T State University, Greensboro, NC 27411, United States. Email: [email protected]